Sales & Support: Request A Quote
Home ProductsMen\'s Health Extracts

cnidium monnieri fruit extract,cnidium monnieri supplements,cnidium fruit osthole

cnidium monnieri fruit extract,cnidium monnieri supplements,cnidium fruit osthole

cnidium monnieri fruit extract,cnidium monnieri supplements,cnidium fruit osthole

Product Details:

Place of Origin: China
Brand Name: Yuhui

Payment & Shipping Terms:

Minimum Order Quantity: 1kg/bag
Packaging Details: 25kg/drum (25kg net weight,28kg gross weight; Packed in a cardboard-drum with two plastic-bags insid
Delivery Time: 3-5 working days after receiving your payment
Payment Terms: Bank transfer, Western Union, Moneygram, Paypal
Supply Ability: 10 tons/month
Contact Now
Detailed Product Description
Product Name: Cnidium Fruit Extract Plant Source: Fructus Cnidii/ Cnidium Monnieri
Active Ingredients: Osthole Specifications: Osthole 10% 35%,50% 80%90%95% 98%
CAS No: 484-12-8 Appearance: Light Yellow To White Powder

Product Introduction:
Cnidium may improve conditions including impotence, female infertility, vaginal itching, and yeast infections. It often causes a deterioration of symptoms in men with chronic spermatorrhea and premature ejaculation. Cnidium has some astringent quality, which means that it will help prevent premature ejaculation in men. Furthermore, Cnidium seed has disinfectant qualities and may be used externally as a wash on sores, particularly in the genital region.
 
Coumarin compounds such as Osthole and Imperatorin as well as Xanthotoxin (Methoxsalen). Isopimpinellin, and Bergapten have also been identified Hydrated berries of Cnidii have concentrations around 1.67-2.88% osthole.
Osthole is commonly seen as the primary active ingredient due to it being the most prominent courmarin derivative in Cnidium Monnieri,and is a coumarin derivative compound. It's true chemical name is 7-methoxy-8{3-methylpent 2-enyl}coumarin.The fruits tend to be used in Traditional Chinese Medicine, but the seeds of Cnidium Monnieri contains these bioactives as well.
 
cnidium monnieri fruit extract,cnidium monnieri supplements,cnidium fruit osthole
Product Description:

Product nameCnidium Fruit Extract
Plant source Fructus Cnidii/ Cnidium monnieri
Latin nameFructus Cnidii
Active IngredientsOsthole
Specifications:Osthole 10% 35%,50% 80%90%95% 98% by HPLC,5:1, 10:1, 20:1
Test methodHPLC
Molecular Formula:C15H16O3
Molecular Weight: 244.29 g/mol
CAS No.: 484-12-8
AppearanceLight yellow to white powder
StandardGMP,Kosher,HALAL,ISO9001.


cnidium extract benefits
 
1. Skin Health
Cnidii Fructus (fruits of Cnidium) have traditionally been used orally as an anti-allergic substance; when testing a variety of traditional herbs (n=33 in total, 6 found to be effective) touted to suppress skin irritation, Cnidium appears to be the most effective in inhibiting substance-P induced itching behaviour in mice.
Through the centuries, traditional Chinese medicine used cnidium to treat skin conditions. Today, it is a popular ingredient in Chinese skin creams, ointments and lotions.
The herb’s antibacterial, antifungal and antipruritic properties make cnidium ideal for skin treatments. Holistic practitioners use the extract for numerous skin conditions including dermatitis, eczema, ringworm, rash and itching.
2. Men's Health
>Skeletal Muscle
Osthole has been implicated in increasing AMPK-mediated glucose uptake into myocytes (both C2C12 and L6) in dose and time dependent manners, although tested mostly at 12.5-50uM and also affects hepatocytes to a less potent extent. Incubation of muscle cells with 12.5uM and 50uM increases glucose uptake via GLUT4 translocation induced by AMPK by 1.6 and 2-fold; respectively. These effects on AMPK may be due to shifting the AMP:ATP ratio, as osthole seems to deplete ATP and elevate relative amounts of AMP, which is known to be the lead inducer of skeletal muscle AMPK.Osthole was known to be anti-glycemic in vivo at 50mg/kg prior to the discovery of AMPK interactions, and was mimicked in streptozotocin-induced diabetic mice at 100mg/kg osthole orally for 8 weeks.
Osthole apparently may also phosphorylate (activate) Akt, and the downstream proteins of AS160 and GSK3; another mechanism by which GLUT4 may be increased.
> Erections
Cnidium Monnieri is, supposedly, a frequently prescribed herb among Chinese Medicine practitioners for male impotence. It has traditionally been used for treatment of male erections (or the lack thereof) alongside Epimedium Sagittatum (related to Horny Goat Weed) and the plant Semen Cuscutae.
When examined in vitro on corpus cavernosum (penis wall) muscles, the bioactive ingredient Osthole appears to be able to cause muscular relaxation (pro-erectile) in a dose-dependent manner. The mechanism may be via phosphodiesterase inhibition, as osthole appears to potentiate cGMP induced relaxation as well as nitric oxide. These effects are common to all coumarins in Cnidium Monnieri, with Imperatorin being requiring the lowest concentration to be effective.
There may also be central (brain) effects as well, due to the ability of osthole to induce glutaminergic neurotransmission (see Neurology section).
Not yet studied in humans, but has traditional usage of being an erection promoting herb in Traditional Chinese Medicine and appears to be active on both the penis tissues and the brain in similar manners to Viagra.
3.Liver Interactions
>Fatty Liver
Osthole is able to reduce fatty liver induced by Alcohol; in a study where mice were fed 52% of caloric intake as ethanol for 4 weeks and then given 10-40mg/kg Osthole for 6 weeks, Osthole was able to normalize alterations in CPT1A and CYP2E1 transcription rates (made abnormal with prolonged alcohol ingestion, and conducive to further fat buildup) and was able to decrease liver fat content in a rehabilitative manner.These effects are also seen when the same dose of osthole is co-ingested, and are attributed to anti-oxidant and anti-inflammatory mechansims, although Osthole does appear to induce PPARa activation which can then reduce DGAT and HMG-CoA activity; a shift towards lipid mobilization rather than storage. Minor dose-dependence is seen, with more Osthole exerting more protection but 10mg/kg seeming to be the most cost-effective dose.
Other
Bodybuilders take cnidium supplements to increase energy and boost athletic performance. Because it improves concentration and memory, the herb is sometimes used to prevent Alzheimer’s disease and other dementias. It is also beneficial for the weak, brittle bones of osteoporosis.
Application:
1. Cnidium Fruit Extract Applied in pharmaceutical field, it is usually made into tablets, capsule and granule to warm the kidney, strengthen the spleen and enhance human immunity.
2. Cnidium Fruit Extract Applied in food field, it is mainly used in kinds of beverage, liquor and foods to enhance human immunity and anti-aging.
Package and shipping
Package: 25kg/drum (25kg net weight,28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside. Drum Size: 510mm high, 350mm diameter) ; 
1kg/bag 
cnidium monnieri fruit extract,cnidium monnieri supplements,cnidium fruit osthole
Shipping: Shipping by Express mail (Fedex, DHL, TNT), Air and Sea. We will deliver the order within 3-5 working days after receiving your payment.

Contact Details
XIAN YUHUI BIOTECHNOLOGY CO.,LTD

Contact Person: Mrs. Jessica

Tel: 86-29-86259572

Fax: 86-29-86259572

Send your inquiry directly to us (0 / 3000)

Other Products